| International Journal of Computer Applications |
| Foundation of Computer Science (FCS), NY, USA |
| Volume 187 - Number 143 |
| Year of Publication: 2026 |
| Authors: Rayala Upendar Rao, Chowdam Naga Kishore |
10.5120/ijca1c80067bdfa8
|
Rayala Upendar Rao, Chowdam Naga Kishore . A Hybrid Ensembled Deep Learning Framework for Explainable Skin Cancer Classification and Lesion Detection. International Journal of Computer Applications. 187, 143 ( Sep 2026), 39-48. DOI=10.5120/ijca1c80067bdfa8
Automated methods for dermoscopy image analysis support the de¬tection of skin cancer in an early stage and reducing skin cancer-related deaths. Deep learning based methods have shown com¬pelling results for the analysis of skin cancer images. In this paper, an enhanced ECRNet-based hybrid model is explored for the clas¬sification and detection of skin cancer and diverse skin anomalies. This model utilizes an ensemble of classification models, namely, ResNet50, ResNet101, MobileNetV2, Vision Transformer, Con-vNeXt, DeiT-Small, EL-DLOA, WavIntNet, Conformer, Xception, VGG16 and an Ensemble of ECRNet and other models. For le¬sion localization, the YOLO model family and Faster R-CNN ar¬chitecture are examined. Experimental results demonstrate that the Hybrid-Ensemble approach outperforms other models with an ac¬curacy of 97.2%, precision of 95.4%, recall of 93.7%, and F1 score of 94.5% while YOLOV26 achieved an mAP of 71.3% with a pre¬cision of 73.9%. Grad-CAM was used to improve the model inter¬pretability by highlighting the image regions containing the lesions. A web application for image upload, automated prediction, and diagnostic visualization was developed using Flask and SQLite.