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3D Microelectrode Geometry Effects the Multilayer Dense Osteo Intra-organelle Membrane Potential Characterization

by S. Sarkar, R. Mahapatra
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International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 80 - Number 17
Year of Publication: 2013
Authors: S. Sarkar, R. Mahapatra
10.5120/13966-1065

S. Sarkar, R. Mahapatra . 3D Microelectrode Geometry Effects the Multilayer Dense Osteo Intra-organelle Membrane Potential Characterization. International Journal of Computer Applications. 80, 17 ( October 2013), 1-9. DOI=10.5120/13966-1065

@article{ 10.5120/13966-1065,
author = { S. Sarkar, R. Mahapatra },
title = { 3D Microelectrode Geometry Effects the Multilayer Dense Osteo Intra-organelle Membrane Potential Characterization },
journal = { International Journal of Computer Applications },
issue_date = { October 2013 },
volume = { 80 },
number = { 17 },
month = { October },
year = { 2013 },
issn = { 0975-8887 },
pages = { 1-9 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume80/number17/13966-1065/ },
doi = { 10.5120/13966-1065 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T21:54:46.181819+05:30
%A S. Sarkar
%A R. Mahapatra
%T 3D Microelectrode Geometry Effects the Multilayer Dense Osteo Intra-organelle Membrane Potential Characterization
%J International Journal of Computer Applications
%@ 0975-8887
%V 80
%N 17
%P 1-9
%D 2013
%I Foundation of Computer Science (FCS), NY, USA
Abstract

We report the computational simulation study for the characterization of multilayer dense osteoblast intra organelle membrane potential in different microelectrode. The response of a cell model at various frequencies and the effect of cell parameters, such as cell membrane resistance and capacitance, were studied. We show that at low frequencies—the intra organelle can be electro porated while at high frequencies, the induced potential can be much lower than that at low frequencies at same applied voltage for dense osteo cells . we also find out that the induced TMP of osteoblast cell depends not only on its radius and geometry of the microelectrode but also the resistances and capacitances of suspending medium, which effects the dielectric property of osteoblast cell.

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Index Terms

Computer Science
Information Sciences

Keywords

Dense cell Osteoblast cells Simulation Electroporation cytoplasm Nucleolus Frequency Response Intra-organelle potential.

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