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Protein Network for Associating Genes with Dementia

by Brijendra Gupta, Ravi Bhushan Mishra
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International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 83 - Number 10
Year of Publication: 2013
Authors: Brijendra Gupta, Ravi Bhushan Mishra
10.5120/14486-2795

Brijendra Gupta, Ravi Bhushan Mishra . Protein Network for Associating Genes with Dementia. International Journal of Computer Applications. 83, 10 ( December 2013), 29-35. DOI=10.5120/14486-2795

@article{ 10.5120/14486-2795,
author = { Brijendra Gupta, Ravi Bhushan Mishra },
title = { Protein Network for Associating Genes with Dementia },
journal = { International Journal of Computer Applications },
issue_date = { December 2013 },
volume = { 83 },
number = { 10 },
month = { December },
year = { 2013 },
issn = { 0975-8887 },
pages = { 29-35 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume83/number10/14486-2795/ },
doi = { 10.5120/14486-2795 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T21:59:30.658846+05:30
%A Brijendra Gupta
%A Ravi Bhushan Mishra
%T Protein Network for Associating Genes with Dementia
%J International Journal of Computer Applications
%@ 0975-8887
%V 83
%N 10
%P 29-35
%D 2013
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Association between causal genes and their genetic diseases is an important problem concerning human health. Linkage analysis is such a method that can identify which unknown disease genes are located in chromosomal region out of hundreds of candidate genes according to their functions, interactions, and pathways which is good identification of genes associated with general/hereditary disorders. Here, we used method for prioritization of candidate genes of Dementia by the use of a global network distance measure, Random Walk Analysis, which detects neurological disorder been associated with distribution of sub-network among the genes.

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Index Terms

Computer Science
Information Sciences

Keywords

Genetic diseases Dementia Random Walk Analysis Neurological disorder .

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