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An Algorithm for Browsing the Referentially-compressed Genomes

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International Journal of Computer Applications
© 2014 by IJCA Journal
Volume 86 - Number 8
Year of Publication: 2014
Authors:
Mohammad Nassef
Amr Badr
Ibrahim Farag
10.5120/15002-3134

Mohammad Nassef, Amr Badr and Ibrahim Farag. Article: An Algorithm for Browsing the Referentially-compressed Genomes. International Journal of Computer Applications 86(8):1-10, January 2014. Full text available. BibTeX

@article{key:article,
	author = {Mohammad Nassef and Amr Badr and Ibrahim Farag},
	title = {Article: An Algorithm for Browsing the Referentially-compressed Genomes},
	journal = {International Journal of Computer Applications},
	year = {2014},
	volume = {86},
	number = {8},
	pages = {1-10},
	month = {January},
	note = {Full text available}
}

Abstract

Genome resequencing produces enormous amount of data daily. Biologists need to frequently mine this data with the provided processing and storage resources. Therefore, it becomes very critical to professionally store this data in order to efficiently browse it in a frequent manner. Reference-based Compression algorithms (RbCs) showed significant genome compression results compared to the traditional text compression algorithms. By avoiding the complete decompression of the compressed genomes, they can be browsed by performing partial decompressions at specific regions, taking lower runtime and storage resources. This paper introduces the inCompressi algorithm that is designed and implemented to efficiently pick sequences from genomes, that are compressed by an existing Reference-based Compression algorithm (RbC), through partial decompressions. Moreover, inCompressi performs a more efficient complete genome decompression compared to the original decompression algorithm. The experimental results showed a significant reduction in both runtime and memory consumption compared to the original algorithm.

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