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Cryptography using DNA Nucleotides

International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Year of Publication: 2017
Mazhar Karimi, Waleej Haider

Mazhar Karimi and Waleej Haider. Cryptography using DNA Nucleotides. International Journal of Computer Applications 168(7):16-18, June 2017. BibTeX

	author = {Mazhar Karimi and Waleej Haider},
	title = {Cryptography using DNA Nucleotides},
	journal = {International Journal of Computer Applications},
	issue_date = {June 2017},
	volume = {168},
	number = {7},
	month = {Jun},
	year = {2017},
	issn = {0975-8887},
	pages = {16-18},
	numpages = {3},
	url = {},
	doi = {10.5120/ijca2017914420},
	publisher = {Foundation of Computer Science (FCS), NY, USA},
	address = {New York, USA}


Cryptography plays a key role in information security. Many new algorithms and techniques have been used in the same regards. Cryptography using DNA computing is very current state of the art. DNA cryptography comes with the next level of data integrity and confidentiality to protect information from intrusions, in this paper a cipher solution is proposed with a new symmetric key generation model based upon DNA strands, nucleotides, codons base pair rules, mutation and DNA to mRNA conversion. This solution emphasizes on usage of biological processes & the random changes found in DNA and simulate those processes in the key generation model.


  1. Adleman, L. M. 1994. Molecular computation of solutions to combinatorial problems.
  2. Chen, J.2003. A DNA-based, bio molecular cryptography design. Circuits and Systems.
  3. Churchhouse, R. F. 2002. Codes and ciphers: Julius Caesar, the Enigma, and the Internet
  4. Hossain, E. M. 2016. A DNA cryptographic technique based on dynamic DNA sequence table.
  5. Leuenberger, M. N. 2001. Quantum computing in molecular magnets.
  6. Li, X.-s. L.-p. 2008. A novel generation key scheme based on DNA.
  7. Needleman, S. B. 1970. A general method applicable to the search for similarities in the amino acid sequence of two proteins.
  8. Ning, K. A. A pseudo DNA cryptography method.
  9. Ochani, A. D. 2016. DNA image encryption using Modified Symmetric Key (MSK).
  10. Varma, P. S. 2014. Cryptography based on DNA using random key generation scheme.
  11. Watson, J. D. 1953. The structure of DNA.


Cryptography, DNA Cryptography, Symmetric Key Generation, Symmetric Key model, Information Security.