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Genetic Algorithm based Optimizer for RNA Secondary Structure Prediction

by Gyan Prakash Sagar, Shailendra Singh, Padmavati
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International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 24 - Number 6
Year of Publication: 2011
Authors: Gyan Prakash Sagar, Shailendra Singh, Padmavati
10.5120/2959-3937

Gyan Prakash Sagar, Shailendra Singh, Padmavati . Genetic Algorithm based Optimizer for RNA Secondary Structure Prediction. International Journal of Computer Applications. 24, 6 ( June 2011), 24-28. DOI=10.5120/2959-3937

@article{ 10.5120/2959-3937,
author = { Gyan Prakash Sagar, Shailendra Singh, Padmavati },
title = { Genetic Algorithm based Optimizer for RNA Secondary Structure Prediction },
journal = { International Journal of Computer Applications },
issue_date = { June 2011 },
volume = { 24 },
number = { 6 },
month = { June },
year = { 2011 },
issn = { 0975-8887 },
pages = { 24-28 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume24/number6/2959-3937/ },
doi = { 10.5120/2959-3937 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T20:10:34.818037+05:30
%A Gyan Prakash Sagar
%A Shailendra Singh
%A Padmavati
%T Genetic Algorithm based Optimizer for RNA Secondary Structure Prediction
%J International Journal of Computer Applications
%@ 0975-8887
%V 24
%N 6
%P 24-28
%D 2011
%I Foundation of Computer Science (FCS), NY, USA
Abstract

The paper represents the optimization of RNA secondary structure prediction in RNA molecule by using the genetic algorithm based on binary crossover operators. Using the selection function STDS keep best reproduction for RNA prediction. Take the number of individual RNA sequence sets from the Rfam family database and calculate the lowest free-energy in the individual RNA sequence sets. Apply the fitness function for optimize the lowest free-energy in the each individual sequence sets. Which one individual sequence set have the lowest free-energy that individual sequence set will be predict the best optimizer secondary structure in the RNA individual sequence and used the RNA fold algorithm for calculating the free-energy in the RNA molecules.

References
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Index Terms

Computer Science
Information Sciences

Keywords

Genetic Algorithm RNA secondary structure RNA folding minimum free-energy Genetic algorithm representation Genetic algorithm crossover operators

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