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Docking Studies of Green Tea Flavonoids as Insulin Mimetics

by Jayasree Ganugapati, Sirisha Mukkavalli, A.Sahithi
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International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 30 - Number 4
Year of Publication: 2011
Authors: Jayasree Ganugapati, Sirisha Mukkavalli, A.Sahithi
10.5120/3627-5063

Jayasree Ganugapati, Sirisha Mukkavalli, A.Sahithi . Docking Studies of Green Tea Flavonoids as Insulin Mimetics. International Journal of Computer Applications. 30, 4 ( September 2011), 48-52. DOI=10.5120/3627-5063

@article{ 10.5120/3627-5063,
author = { Jayasree Ganugapati, Sirisha Mukkavalli, A.Sahithi },
title = { Docking Studies of Green Tea Flavonoids as Insulin Mimetics },
journal = { International Journal of Computer Applications },
issue_date = { September 2011 },
volume = { 30 },
number = { 4 },
month = { September },
year = { 2011 },
issn = { 0975-8887 },
pages = { 48-52 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume30/number4/3627-5063/ },
doi = { 10.5120/3627-5063 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T20:16:07.975769+05:30
%A Jayasree Ganugapati
%A Sirisha Mukkavalli
%A A.Sahithi
%T Docking Studies of Green Tea Flavonoids as Insulin Mimetics
%J International Journal of Computer Applications
%@ 0975-8887
%V 30
%N 4
%P 48-52
%D 2011
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Diabetes Mellitus is a metabolism disorder where glucose, principal source of energy cannot enter the cells due to deficiency of insulin. In the present study, insilico approach was used to asses the use of natural green tea flavonoids as potential agents that could act as insulin receptor activators and reduce the harmful effects of diabetes. Docking studies of green tea flavanoids were carried out using Auto Dock 4.0 and Argus lab 4.0.1. Analysis of the results of both the docking softwares suggested that epicatechin can act as a potent insulin receptor activator.

References
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Index Terms

Computer Science
Information Sciences

Keywords

Green tea flavonoids Diabetes mellitus Interdisciplinary Research Applications of Computer Science Techniques for medical diagnosis Docking AUTO DOCK

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