CFP last date
20 June 2024
Reseach Article

Underlying Effect of miRNA Patterns for Identification of Human Diseases

Published on May 2014 by Ranjeet Kumar Rout, Pabitra Pal Choudhury, Beauty Barman, Saurabh Singh, Uttari Chakraborty
National Conference cum Workshop on Bioinformatics and Computational Biology
Foundation of Computer Science USA
NCWBCB - Number 1
May 2014
Authors: Ranjeet Kumar Rout, Pabitra Pal Choudhury, Beauty Barman, Saurabh Singh, Uttari Chakraborty
ddf254c7-4021-4c52-afac-abcbc6fb1420

Ranjeet Kumar Rout, Pabitra Pal Choudhury, Beauty Barman, Saurabh Singh, Uttari Chakraborty . Underlying Effect of miRNA Patterns for Identification of Human Diseases. National Conference cum Workshop on Bioinformatics and Computational Biology. NCWBCB, 1 (May 2014), 18-20.

@article{
author = { Ranjeet Kumar Rout, Pabitra Pal Choudhury, Beauty Barman, Saurabh Singh, Uttari Chakraborty },
title = { Underlying Effect of miRNA Patterns for Identification of Human Diseases },
journal = { National Conference cum Workshop on Bioinformatics and Computational Biology },
issue_date = { May 2014 },
volume = { NCWBCB },
number = { 1 },
month = { May },
year = { 2014 },
issn = 0975-8887,
pages = { 18-20 },
numpages = 3,
url = { /proceedings/ncwbcb/number1/16507-1407/ },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Proceeding Article
%1 National Conference cum Workshop on Bioinformatics and Computational Biology
%A Ranjeet Kumar Rout
%A Pabitra Pal Choudhury
%A Beauty Barman
%A Saurabh Singh
%A Uttari Chakraborty
%T Underlying Effect of miRNA Patterns for Identification of Human Diseases
%J National Conference cum Workshop on Bioinformatics and Computational Biology
%@ 0975-8887
%V NCWBCB
%N 1
%P 18-20
%D 2014
%I International Journal of Computer Applications
Abstract

MicroRNAs (miRNAs) originally an unappreciated class of small ribonucleic acids (RNAs) were diagnosed as moderate biological modifiers. Over the years rigorous research on microRNAs established them as a powerful regulator of various cellular processes like occurrence of different diseases. In this paper cellular automata approach is used by replacing the miRNA sequences with binary forms and using an evolutionary rule those sequences can be converted into distinct images. This is immensely helpful as the cellular automata images of the miRNA sequences help in deciphering various vital aspects which were previously unknown and thereby rendering it possible to find a pattern. Using this concept it becomes easier to distinguish amongst the different miRNA images and hence identify the influence of the segments of the miRNA sequences on the pattern of the corresponding images.

References
  1. X. Xiao et al. Bio-Informatics Research Center, "Using cellular automata to generate image representation for biological sequences",( 2005)Amino Acids. Vol. 28,( 2005) I-1, pp 29-35 .
  2. X. Xiao et al. Bioinformatics Research Center. "Using cellular automata images and pseudo amino acid composition to predict protein subcellular location" (2006) Amino Acids. , Vol. 30,( 2006) I-1, pp 49-54.
  3. Stephen Wolfram; Statistical Mechanics Cellular Automata; (1983)Reviews of Modern Physics, Vol. 55,.
  4. E. v. Rooij; The Art of MicroRNA Research; (2011)Circulation Research Journal of The American Heart Association, 108(2)( 2011):219-34. doi: 10. 1161/CIRCRESAHA. 110. 227496Tavel, P. 2007 Modeling and Simulation Design. AK Peters Ltd.
  5. Sannella, M. J. 1994 Constraint Satisfaction and Debugging for Interactive User Interfaces. Doctoral Thesis. UMI Order Number: UMI Order No. GAX95-09398. , University of Washington.
  6. M. Lu, Q. Zhang, M. Deng, J. Miao, Y. Guo, An Analysis of Human MicroRNA and Disease Associations. PLoS ONE 3(10)(2008) e3420. doi:10. 1371/journal. pone. 0003420
  7. Xi Chenet et. al, "Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases",(2008). Cell Research Cell Research (2008) 18:997–1006. doi: 10. 1038/cr. 2008. 282.
  8. S. WolForm, "A New Kind of Science", (2002)Wolfram Media, Inc. ,
  9. D. P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell, 116 (2004), pp. 281–297.
  10. Hu Xiaoxia, J. K. Schwarz, J. S. Lewis Jr. et al. A microRNA expression signature for cervical cancer progression Cancer Res. , 70 (2010), pp. 1441–1448.
  11. G. Reshmi, P. M. Radhakrishna Beyond HPV: Oncomirs as new players in cervical cancer FEBS Lett. , 582 (2008), pp. 4113–4116
  12. P. Maji and P. P. Chaudhuri, "Fuzzy Cellular Automata for Modeling Pattern Classifier," IEICE, (2004).
  13. P. Maji and P. P. Chaudhuri (2004), FMACA: A Fuzzy Cellular Automata Based Pattern Classifier, Proceedings of 9th International Conference on Database Systems, Korea, pp. 494–505, 2004.
Index Terms

Computer Science
Information Sciences

Keywords

Mirna Cellular Automata State Space Images.