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M-FISH Image Segmentation and Classification using Fuzzy Logic

by Lijiya A, Sreejithlal G S, Govindan V K
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International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 70 - Number 25
Year of Publication: 2013
Authors: Lijiya A, Sreejithlal G S, Govindan V K
10.5120/12227-8519

Lijiya A, Sreejithlal G S, Govindan V K . M-FISH Image Segmentation and Classification using Fuzzy Logic. International Journal of Computer Applications. 70, 25 ( May 2013), 46-51. DOI=10.5120/12227-8519

@article{ 10.5120/12227-8519,
author = { Lijiya A, Sreejithlal G S, Govindan V K },
title = { M-FISH Image Segmentation and Classification using Fuzzy Logic },
journal = { International Journal of Computer Applications },
issue_date = { May 2013 },
volume = { 70 },
number = { 25 },
month = { May },
year = { 2013 },
issn = { 0975-8887 },
pages = { 46-51 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume70/number25/12227-8519/ },
doi = { 10.5120/12227-8519 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T21:33:51.508713+05:30
%A Lijiya A
%A Sreejithlal G S
%A Govindan V K
%T M-FISH Image Segmentation and Classification using Fuzzy Logic
%J International Journal of Computer Applications
%@ 0975-8887
%V 70
%N 25
%P 46-51
%D 2013
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Karyotyping has an important role in identifying genetic disorders due to structural changes in chromosomes. Multiplex fluorescence in-situ hybridization (M-FISH) technique provides more precise karyotyping. The new classification method, proposed in this paper, automates karyotyping, based on Fuzzy c-means (FCM) algorithm combined with a labeling chart. Classification results show that the proposed method improves accuracy and running time. It is also observed that the accuracy of classification can further be improved, using a new Reclassification algorithm which reduces the chance of wrongly classified chromosome pixels.

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Index Terms

Computer Science
Information Sciences

Keywords

Karyotyping Multiplex fluorescence in-situ hybridization (M-FISH) Fuzzy c-means (FCM) Labeling chart Reclassification

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